1. Match List-I with List-II
| List-I | List-II |
| (a) S phase (b) G2 phase (c) Quiescent stage (d) G1 phase | I. Proteins are synthesized II. Inactive phase III. Interval between mitosis and initiation of DNA replication IV. DNA replication |
Choose the correct answer from the options given below.
(a) (b) (c) (d)
1. (iv) (i) (ii) (iii)
2. (ii) (iv) (iii) (i)
3. (iii) (ii) (i) (iv)
4. (iv) (ii) (iii) (i)
2. The centriole undergoes duplication during:
(1) Metaphase
(2) G2 phase
(3) S-phase
(4) Prophase
3. The fruit fly has 8 chromosomes (2n) in each cell. During the interphase of Mitosis if the number of chromosomes at G1 phase is 8, what would be the number of chromosomes after the S phase?
1. 4
2. 32
3. 8
4. 16
4. Some dividing cells exit the cell cycle and enter the vegetative inactive stage. This is called the quiescent stage G0. This process occurs at the end of:
1. G1 phase
2. S phase
3. G2 phase
4. M phase
5. Identify the correct statement with regard to G1 phase (Gap 1) of interphase.
1. The reorganisation of all cell components takes place.
2. The cell is metabolically active, grow but does not replicate its DNA
3. Nuclear Division takes place
4. DNA synthesis or replication takes place.
6. In a mitotic cycle, the correct sequence of phases is
1. S, G1, G2, M
2. G1, S, G2, M
3. M, G1, G2, S
4. G1, G2, S, M
7. Match the following events that occur in their respective phases of cell cycle and select the correct option:
(a) G 1 phase (i) Cell grows and organelle duplication
(b) S phase (ii) DNA replication and chromosome duplication
(c) G 2 phase (iii) Cytoplasmic growth
(d) Metaphase in M-phase (iv) Alignment of chromosomes
1. (a)-(ii), (b)-(iii), (c)-(iv), (d)-(i)
2. (a)-(iii), (b)-(iv), (c)-(i), (d)-(ii)
3. (a)-(iv), (b)-(i), (c)-(ii), (d)-(iii)
4. (a)-(iii), (b)-(ii), (c)-(i), (d)-(iv)
8. Cells in G0 phase:
1. terminate the cell cycle
2. exit the cell cycle
3. enter the cell cycle
4. suspend the cell cycle
9. During cell growth, DNA synthesis takes place in
1. S-phase
2. G1-phase
3. G2 -phase
4. M-phase
10. Match the following column I with column II.
| Column I | Column II |
| A. Synapsis aligns homologous chromosomes | (i) Anaphase II |
| B. Synthesis of RNA and protein | (ii) Zygotene |
| C. Action of enzyme recombinase | (iii) G2 - phase |
| D. Centromeres do not separate, but chromatids move towards opposite poles | (iv) Anaphase I |
| (v) Pachytene |
1. A-(ii) B-(i) C-(iii) D-(iv)
2. A-(ii) B-(iii) C-(v) D-(iv)
3. A-(i) B-(ii) C-(v) D-(iv)
4. A-(ii) B-(iii) C-(iv) D-(v)
11. During which phase(s) of cell cycle, amount of DNA in a cell remains at 4 C level if the initial amount is denoted as 2C ?
1. G0 and G1
2. G1 and S
3. Only G2
4. G2 and M
12. In 'S' phase of the cell cycle
1. amount of DNA doubles in each cell.
2. amount of DNA remains same in each cell
3. chromosome number is increased
4. amount of DNA is reduced to half in each cell.
13. In the somatic cell cycle: -
1. DNA replication takes place in S-phase
2. A short interphase is followed by a long mitotic phase
3. G2phase follows mitotic phase
4. In G1 phase, DNA content is double the amount of DNA present in the original cell
14. Best material for the study of mitosis in laboratory: -
(1) Anther
(2) Root tip
(3) Leaf tip
(4) Ovary
15. In which stage of cell cycle, DNA replication occurs:
1. G1 - phase
2. S - phase
3. G2 - phase
4. M - phase
| Question | Answer |
| 1. | 1 |
| 2. | 3 |
| 3. | 3 |
| 4. | 1 |
| 5. | 2 |
| 6. | 2 |
| 7. | 4 |
| 8. | 4 |
| 9. | 1 |
| 10. | 2 |
| 11. | 4 |
| 12. | 1 |
| 13. | 1 |
| 14. | 2 |
| 15. | 2 |
1. Attachment of spindle fibers to kinetochores of chromosomes becomes evident in:
1. Anaphase
2. Telophase
3. Prophase
4. Metaphase
2. Which of the following options gives the correct sequence of events during mitosis?
1. Condensation, nuclear membrane disassembly, arrangement at equator, centromere division, segregation, telophase
2. Condensation, crossing over, nuclear membrane disassembly, segregation, telophase
3. Condensation, centromere division, segregation, arrangement at equator, telophase
4. Condensation, nuclear membrane disassembly, crossing over, segregation, telophase
3. Which of the following is not a characteristic feature during mitosis cells ?
1. Disappearance of nucleolus
2. Chromosome movement
3. Synapsis
4. Spindle fibres
4. Spindle fibres attach on to
1. kinetochore of the chromosome
2. centromere of the chromosome
3. kinetosome of the chromosome
4. telomere of the chromosome
5. A stage in cell division is shown in the figure. Select the answer which gives the correct identification of the stage with its characteristics:
| 1. | Late anaphase | Chromosomes move away from the equatorial plate, Golgi complex not present |
| 2. | Cytokinesis | Cell plate formed, mitochondria distributed between two daughter cells |
| 3. | Telophase | Endoplasmic reticulum and nucleolus not reformed yet |
| 4. | Telophase | Nuclear envelop reforms, Golgi complex reforms |
6. Identify the meiotic stage in which the homologous chromosomes separate while the sister chromatids remain associated at their centromeres:
1. Metaphase-II
2. Anaphase-I
3. Anaphase-II
4. Metaphase-I
7. Select the correct option with respect to mitosis.
1. Chromatids start moving towards opposite poles in telophase.
2. Golgi complex and endoplasmic reticulum are still visible at the end of prophase.
3. Chromosomes move to the spindle equator and get aligned along equatorial plate in metaphase.
4. Chromatids separate but remain in the center of the cell in anaphase.
8. At metaphase, chromosomes are attached to the spindle fibres by their :
1. Centromere
2. Satellites
3. Secondary constrictions
4. Kinetochores
9. During mitosis ER and nucleolus begin to disappear at
1. late prophase
2. early metaphase
3. late metaphase
4. early prophase
10. Which stages of cell division do the following figures A and B represent respectively?
1. Metaphase- Telophase
2. Telophase- Metaphase
3. Late anaphase- Prophase
4. Prophase- Anaphase
11. Centromere is required for -
(1) Movement of chromosomes towards poles
(2) Cytoplasmic cleavage
(3) Crossing over
(4) Transcription
12. If you are provided with root-tips of onion in your class and are asked to count the chromosomes, which of the following stages can you most conveniently look into?
1. Telophase
2. Anaphase
3. Prophase
4. Metaphase
13. Spindle fibre unites with which structure of chromosomes:
1. Chromocenter
2. Chromomere
3. Kinetochore
4. Centriole
14. Which one of the following never occurs during mitotic cell division?
1. Coiling and condensation chromatids
2. Spindle fibres attach to Kinetochores of chromosomes
3. Movement of centrioles towards opposite poles
4. Pairing of homologous chromosomes
15. Select the incorrect statement with reference to mitosis:
1. Splitting of centromere occurs at anaphase.
2. All the chromosomes lie at the equator at metaphase.
3. Spindle fibres attach to centromere of chromosomes.
4. Chromosomes decondense at telophase
16. Given below are two statements : One is labelled as Assertion (A) and the other is labelled as Reason (R)
Assertion (A): The growth of multicellular organism is due to mitosis
Reason (R) Mitosis is also called as equational division and it offers genetic stability
In the light of the above statements choose the correct answer from the options given below:
1. (A) is correct but (R is not correct
2. (A) is not correct but R is correct
3. Both (A) and (R) are correct and (R) is the correct explanation of (A)
4. Both (A) and (R) are correct and (R) is not the correct explanation of (A)
(17) Given below are two statements : One is labelled as Assertion (A) and the other is labelled as Reason (R)
Assertion (A): The growth of multicellular organism is due to mitosis
Reason (R) Mitosis is also called as equational division and it offers genetic stability
In the light of the above statements choose the correct answer from the options given below:
1. (A) is correct but (R is not correct
2. (A) is not correct but R is correct
3. Both (A) and (R) are correct and (R) is the correct explanation of (A)
4. Both (A) and (R) are correct and (R) is not the correct explanation of (A)
| Question | Answer |
| 1. | 4 |
| 2. | 1 |
| 3. | 3 |
| 4. | 1 |
| 5. | 4 |
| 6. | 2 |
| 7. | 3 |
| 8. | 4 |
| 9. | 4 |
| 10. | 3 |
| 11. | 1 |
| 12. | 4 |
| 13. | 3 |
| 14. | 4 |
| 15. | 3 |
| 16. | 3 |
| 17. | 3 |
(1) Which stage of meiotic prophase shows terminalisation of chiasmata as its distinctive feature?
1. Diakinesis
2. Pachytene
3. Leptotene
4. Zygotene
(2) Dissolution of the synaptonemal complex occurs during :
1. Zygote
2. Diplotene
3. Leptotene
4. Pachytene
(3) Match the following with respect to meiosis:
a. Zygotene i. Terminalization
b. Pachytene ii. Chiasmata
c. Diplotene iii. Crossing over
d. Diakinesis iv. Synapsis
Select the correct option from the following:
(a) (b) (c) (d)
1. iv iii ii i
2. i ii iv iii
3. ii iv iii i
4. iii iv i ii
(4) During Meiosis 1, in which stage synapsis takes place?
1. Pachytene
2. Zygotene
3. Diplotene
4. Leptotene
(5) Crossing over takes place between which chromatids and in which stage of the cell cycle?
1. Non-sister chromatids of non-homologous chromosomes at Zygotene stage of prophase I.
2. Non-sister chromatids of homologous chromosomes at Pachytene stage of prophase I.
3. Non-sister chromatids of homologous chromosomes at Zygotene stage of prophase I.
4. Non-sister chromatids of non-homologous chromosomes at Pachytene stage of prophase I.
(6) The stage during which separation of the paired homologous chromosomes begins is
1. Pachytene
2. Diplotene
3. Diakinesis
4. Zygotene
(7) Match the stages of meiosis in Column I to their characteristic features in Column II and select the correct option using the codes given below :
| Column I | Column II |
| a. pachytene | 1. pairing of homologous chromosomes |
| b. metaphase - 1 | 2. terminalisation of chiasmata |
| c. diakinesis | 3. crossing - over takes place |
| d. zygotene | 4. chromosomes align at equatorial plate |
1. a-3 b-4 c-2 d-1
2. a-1 b-4 c-2 d-3
3. a-2 b-4 c-3 d-1
4. a-4 b-3 c-2 d-1
(8) In meiosis crossing over is initiated at
1. leptotene
2. zygotene
3. diplotene
4. Pachytene
(9) Arrange the following events of meiosis in correct Sequences
I. Crossing over
II. Synapsis
III. Terminalisation of chiasmata
IV. Disappearance of nucleolus
1. II,I,IV,III
2. II,I,III,IV
3. I,II,III,IV
4. II,III,IV,I
10. Match the following column I with column II.
| Column I | Column II |
| A. Synapsis aligns homologous chromosomes | (i) Anaphase II |
| B. Synthesis of RNA and protein | (ii) Zygotene |
| C. Action of enzyme recombinase | (iii) G2 - phase |
| D. Centromeres do not separate, but chromatids move towards opposite poles | (iv) Anaphase I |
| (v) Pachytene |
1. A-(ii) B-(i) C-(iii) D-(iv)
2. A-(ii) B-(iii) C-(v) D-(iv)
3. A-(i) B-(ii) C-(v) D-(iv)
4. A-(ii) B-(iii) C-(iv) D-(v)
(11) The enzyme recombinase is required at which stage of meiosis
1. Pachytene
2. Zygotene
3. Dipotene
4. Diakenesis
(12) The complex formed by a pair of synapsed homologous chromosomes is called
1. Kinetochore
2. Bivalent
3. Axoneme
4. Equatorial plate
(13) During gamete formation, the enzyme recombinase participates during
1. Metaphase-I
2. Anaphase-II
3. Prophase-I
4. Prophase-II
(14) During gamete formation, the enzyme recombinase participates during
1. Metaphase-I
2. Anaphase-II
3. Prophase-I
4. Prophase-II
(15) Crossing over that results in genetic recombination in higher organisms occurs between:-
1. Non-sister chromatids of a bivalent
2. Two daughter nuclei
3. Two different bivalents
4. Sister chromatids of a bivalents
(16) Amount of cellular DNA increases during:
1. Cytokinesis
2. Fertilisation
3. Mutation
4. Respiration
(17) Amount of cellular DNA increases during :
1. Cytokinesis
2. Fertilisation
3. Mutation
4. Respiration
(18) The appearance of recombination nodules on homologous chromosomes during meiosis characterizes:
1. Terminalization
2. Synaptonemal complex
3. Bivalent
4. Sites at which crossing over occurs
(19) Regarding Meiosis, which of the statement is incorrect ?
1. Four haploid cells are formed at the end of Meiosis-II
2. There are two stage in Meiosis, Meiosis-I and II
3. DNA replication occurs in S phase of Meiosis-II
4. Pairing of homologous chromosomes and recombination occurs in Meiosis-I
(20) In prophase I of Meiosis, chromosomes start pairing together and synapsis takes place. This process occurs during which of the following stage?
1. Pachytene
2. Diplotene
3. Leptotene
4. Zygotene
(21) Given below are two statements: One is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A): The beginning of diplotene is recognised by the dissolution of the synaptonemal complex and formation of X shaped structures called chiasmata
Reason(R): In oocytes of some vertebrates, diplotene can last for months or years. In the light of the above statements, choose the correct answer from the options given below:
1. (A) is correct but (R) is not correct
2. (A) is not correct but (R) is correct
3. Both (A) and (R) are correct and (R) is the correct explanation of (A)
4. Both (A) and (R) are correct but (R) is not the correct explanation of (A)
(22) The oocytes of some vertebrates get arrested for years or months in:
1. Telophase - I
2. Diplotene
3. Diakinesis
4. Metaphase - I
(23) Select the correct sequence of events occurring during Prophase-I of Meiosis-I:
(a) Nuclear envelope breakdown
(b) Synaptonemal complex formation
(c) Compaction of chromosomes
(d) Terminalisation of chiasmata
(e) Crossing over
Choose the most appropriate answer from the options given below:
1. (c) → (b) → (e) → (d) → (a)
2. (c) → (a) → (b) → (d) → (e)
3. (b) → (c) → (a) → (d) → (e)
4. (c) → (a) → (b) → (e) → (d)
(24) Which stage of meiosis can last for months or years in the oocytes of some vertebrates?
1. Leptotene
2. Pachytene
3. Diplotene
4. Diakinesis
(25) In meiosis, crossing over and exchange of genetic material between homologous chromosomes are catalyzed by the enzyme.
1. Phosphorylase
2. Recombinase
3. Transferase
4. Polymerase
(26) Identify the correct sequence of events during Prophase I of meiosis :
a. Synapsis of homologous chromosomes
b. Chromosomes become gradually visible under microscope
c. Crossing over between non-sister chromatids of homologous chromosomes
d. Terminalisation of chiasmata
e. Dissolution of synaptonemal complex
Choose the correct answer from the options given below :
1. (a), (b), (c), (d), (e)
2. (b), (c), (d), (e), (a)
3. (b), (a), (c), (e), (d)
4. (a), (c), (d), (e), (b)
(27) Bivalent or Tetrad formation is a characteristic feature observed during :
1. Synaptonemal complex in zygotene stage
2. Chiasmata in Diplotene stage
3. Synaptonemal complex in Pachytene stage
4. Chiasmata in zygotene stage
| Question | Answer |
| 1. | 1 |
| 2. | 2 |
| 3. | 1 |
| 4. | 2 |
| 5. | 2 |
| 6. | 2 |
| 7. | 1 |
| 8. | 4 |
| 9. | 2 |
| 10. | 2 |
| 11. | 1 |
| 12. | 2 |
| 13. | 3 |
| 14. | 4 |
| 15. | 1 |
| 16. | 2 |
| 17. | 1 |
| 18. | 4 |
| 19. | 3 |
| 20. | 4 |
| 21. | 4 |
| 22. | 2 |
| 23. | 1 |
| 24. | 3 |
| 25. | 2 |
| 26. | 3 |
| 27. | 1 |
(1) Which of the following stages of meiosis involves division of centromere?
1. Anaphase II
2. Telophase II
3. Metaphase I
4. Metaphase II
(2) Match the following column I with column II.
| Column I | Column II |
| A. Synapsis aligns homologous chromosomes | (i) Anaphase II |
| B. Synthesis of RNA and protein | (ii) Zygotene |
| C. Action of enzyme recombinase | (iii) G2 - phase |
| D. Centromeres do not separate, but chromatids move towards opposite poles | (iv) Anaphase I |
| (v) Pachytene |
1. A-(ii) B-(i) C-(iii) D-(iv)
2. A-(ii) B-(iii) C-(v) D-(iv)
3. A-(i) B-(ii) C-(v) D-(iv)
4. A-(ii) B-(iii) C-(iv) D-(v)
(3) Regarding Meiosis, which of the statement is incorrect ?
1. Four haploid cells are formed at the end of Meiosis-II
2. There are two stage in Meiosis, Meiosis-I and II
3. DNA replication occurs in S phase of Meiosis-II
4. Pairing of homologous chromosomes and recombination occurs in Meiosis-I
| Question | Answer |
| 1. | 1 |
| 2. | 2 |
| 3. | 3 |
